Monkeypox virus was first identified in Denmark in 1958. It was first seen in humans in 1970 in a 9-month-old male baby in the Democratic Republic of Congo. Monkeypox virus belongs to the orthopoxvirus genus within the pox virus family. This virus is detected locally and multiplies in the area where it is found, causing inflammation. It is carried to the lymph nodes, spleen, tonsils and bone marrow through the circulation in this region. The viruses that multiply here then reach target organs such as testicles and skin. The most common clinical symptoms of monkeypox virus disease are fever, fatigue, lymphadenopathy, and widespread rash all over the body. These rashes, which can be seen all over the body, including the mouth, genital area, palms and soles of the feet, start as macular and turn into papular, vesicular and pustular forms, respectively and these rashes end up crusting. This virus affects the skin, respiratory system, urogenital system, digestive system, nervous system and eyes in different ways and causes problems.