The COVID-19 pandemic has had significant economic impacts worldwide. The pandemic has also caused serious effects on businesses, which are one of the key elements of the economy. Although a few sectors benefited from the pandemic, the majority experienced significant negative impacts. One of the sectors affected by the pandemic is the energy sector. The energy sector stands out as an important industry due to its role in sustaining daily life and its direct and indirect connections with other sectors. Based on this, this study investigates the impact of the COVID-19 pandemic on the determinants of the financial performance of businesses in the energy sector. The data for the study were compiled from the financial statements of the 20 largest energy companies by market capitalization listed on the U.S. stock exchanges, and these data were analyzed using the multiple linear regression analysis method. The results of the study reveal that the COVID-19 pandemic had significant effects on the determinants of financial performance in energy companies.