In recent years, rapid population growth worldwide has led to the unplanned expansion of settlements. This situation has resulted in various problems in the natural environment. To address these issues, it is necessary to conduct studies that consider natural environmental ingredients in the selection of suitable locations for settlements. In this study, it is aimed to evaluate the suitability for settlement in terms of natural environmental ingredients by using a GIS-supported analysis and Analytical Hierarchy Process (AHP) method of 5000 Evler district, which is located in the central district of Karabük and consists of 3 neighborhoods. For this, areas suitable for settlement have been identified using factors of geology, hydrogeology, land use, elevation, slope, aspect, distance to fault lines, landslide risk, distance to rivers, ground acceleration, distance to roads, temperature and precipitation. With the obtained weights, a weighted overlay analysis is performed using GIS software, where all layers are overlaid, resulting in the production of a suitability map for the study area. The produced settlement suitability map generated is divided into two different classes: moderate and low sensitivity. According to the obtained results, in terms of suitability for settlement in the study area, it is observed that areas with moderate sensitivity cover 301.42 hectares, while areas with low sensitivity cover 20.82 hectares. The results obtained from this study are expected to assist decision-makers in future land management efforts in the study area and its surroundings. This study also emphasizes that GIS-based MCDA and AHP methods are very powerful methods in producing settlement suitability maps.