This book chapter delves into the fascinating and extensive applications of composite materials synthesized in biomimetic nanohybrid structures in the fields of analytical chemistry, surface chemistry, and corrosion. The chapter introduces the advantages of these materials over traditional ones, including their exceptional mechanical, thermal, and optical properties, high surface area-to-volume ratio, and enhanced resistance to corrosion. The synthesis methods used to create composite materials in biomimetic nanohybrid structures are also discussed, with examples including layer-by-layer assembly, in situ polymerization, and sol-gel processes. The chapter then proceeds to examine the potential benefits of these materials in analytical chemistry, where they offer improved sensitivity and selectivity, as well as examples of their use in sensors and separation techniques. In surface chemistry, composite materials in biomimetic nanohybrid structures can enhance properties such as adhesion and durability, and their application in areas such as coatings and catalysis is discussed. Furthermore, the chapter highlights the importance of composite materials in biomimetic nanohybrid structures in corrosion prevention, where they offer enhanced resistance to corrosion. Examples are given of their use in corrosion-resistant coatings and materials. The chapter concludes with a summary of the potential future developments and applications of these materials, highlighting their potential to revolutionize various fields, including biotechnology, energy, and materials science.