It is very important to develop and research the machinability properties of St37 steel, which is highly preferred in the manufacturing industry. During the milling of these materials, the use of the minimum quantity lubrication (MQL) cooling/lubrication system is increasing day by day, but the effects of the variable parameters included in this system on the milling process have not been sufficiently investigated. In addition, the effect of spray distance, which is one of the variable parameters of this system, on the machinability metrics is also a matter of curiosity. For this reason, in this study, the cutting depth (1 mm) of St37 plain carbon steel, which has a common usage area, is kept constant, and the CNC milling process is performed by using MQL-assisted cooling at different cutting speeds (140-210 m/min) and feed rates (0.14-0.21 mm/rev) was carried out. In the study, the effects of different cutting and feed rates and different MQL spray distances (50-250 mm) on the output parameters (Surface roughness, tool wear, and cutting temperature) in machinability were investigated. According to the findings, it was seen that MQL fluid applied from a long distance had a positive effect on tool wear and cutting temperature. It was determined that the effect of MQL application distance on the surface roughness varies depending on the cutting speed.