The relationship between genetics and nutrition plays a crucial role in determining an individual’s metabolism, energy utilization, and physical performance. Genetic factors influence muscle structure and energy metabolism, affecting endurance, strength capacity, and recovery processes. The genetic-based approach to nutrition for performance enhancement allows individuals to optimize their physical capacity through personalized dietary strategies. Moreover, integrating nutrition strategies with genetic factors in injury prevention and recovery can accelerate tissue repair and reduce the risk of injuries. The widespread adoption of genetic testing and personalized nutrition applications holds significant potential for athlete health and performance optimization.