The Importance of Antioxidants in Patients with Acute Pancreatitis
Chapter from the book:
Demir,
H.
(ed.)
2024.
Current Research in the Field of Biochemistry.
Synopsis
Acute pancreatitis (AP) is a severe inflammation of the pancreas that causes pancreatic enzyme activation, autolysis, and local and systemic inflammation. The prevalence of AP is increasing worldwide. Despite advances in diagnosis and treatment, AP continues to cause significant morbidity and mortality. Various factors, such as alcohol intake and bile duct obstruction, may play a role in the development of AP. If the causative factor is treated promptly, both the structure and activity of the pancreas can return to normal. However, AP can be a life-threatening disease. For example, severe AP can alter the function and structure of the pancreatic duct, eventually leading to chronic obstructive pancreatitis. The current state-of-the-art treatment for AP primarily consists of supportive care, including monitoring of vital signs and arterial oxygen saturation, fluid resuscitation, and analgesic therapy. In addition, effective antioxidant therapy, which can reduce oxidative stress, may represent an additional therapeutic option to current treatments for patients with AP. Recent research has focused on the link between antioxidants and many diseases. Oxidative stress is caused by an imbalance between free radicals and antioxidant defense mechanisms in the body. There may be antioxidants that can eliminate this and protect Aβ from many diseases.
As a result, the relationship between Acute pancreatitis (AP) and Antioxidants was examined and it was concluded that consuming foods containing sufficient antioxidants that can help prevent Aβ disease may be beneficial.