In recent years, amazing developments have been experienced in molecular modeling with advancing computer infrastructures and bioinformatics technologies. Considering the time and costs required to transform a chemical into a potential drug, Computer Aided Drug Design (CADD) used in molecular modeling methods is at the forefront. The most important example of this situation is the Covid 19 pandemic in our country and around the world. The rapid spread of the disease and the need for active pharmaceutical ingredients to be rapidly developed for the disease itself and its symptoms have led to the necessity of placing drugs on the market as soon as possible. CADD methods have gained more importance in this pandemic and have become a solution to the situation. In this section, molecular modeling and CADD methods have been tried to be explained with brief information. Additionally, the free Autodock Vina program, which is frequently used in molecular docking methods, has been examined and the main steps in its use have been stated. In addition, it was shared which drugs were developed using these methods in the pharmaceutical market.