This study was carried out to investigate university students’ psychological well-being in terms of various variables. The predictive role of problematic internet use, internet use purposes, daily internet usage time, the most frequently time period of internet usage and gender in psychological well-being was examined. Participants of the study were 1927 students attending to the various faculties of Anadolu University. The data were collected by Psychological Well-being Scale, Problematic Internet Use Scale, and Personal Information Form. The data were analyzed using descriptive statistics, correlation and stepwise regression. As a result of stepwise regression analysis, it was found that problematic internet use, gender, the most frequently time period of internet usage and the purpose of internet use are significant predictors of psychological well-being. In the discussion section, explanations related to the findings and suggestions for future research were provided.