Heterocyclic compounds constitute the largest and most important category of organic chemistry. Heterocyclic compounds constitute 80% of the drugs available on the market. There are mostly 5-membered heterocyclic compounds in the structure of natural compounds, vitamins, nucleic acids, hormones and synthetic drugs. Many of the methods used to synthesize heterocyclic compounds are not sustainable. In recent years, it has started to use the microwave method to synthesize many compounds more effectively, including nitrogen-containing five-membered heterocyclic compounds. The microwave method provides great advantages over traditional heating methods such as homogeneous heat distribution, cleaner chemistry, improved yields, reduction in reaction times, and higher product quality.