Myocardial infarction (MI) is an irreversible cardiac necrosis that develops due to sudden cessation of blood flow as a result of occlusion of one or more of the narrowed coronary arteries. Cardiac biomarkers are laboratory tests used to detect acute myocardial infarction or myocardial damage. Since myocardium causes cell destruction, it causes some proteins present in the cell to be included in the general circulation. Among these proteins, enzymes have an important place. Biomarkers are proteins or enzymes such as lactate dehydrogenase, myoglobin, creatine kinase MB, troponin, which occur due to myocardial ischemia or necrosis. The use of cardiac biomarkers is important for early diagnosis and risk determination in coronary diseases. Mediators that play a role in the course of the disease may be potential treatment targets.